【摘要】目的探讨白细胞非升高性上呼吸道感染的抗生素治疗及中药治疗效果, 以提高合理用药。方法对858例白细胞非升高性上呼吸道感染患者进行分组治疗观察, 随机分为抗生素治疗组429例和中药治疗组429例。两组均采用一般支持和对症治疗, 抗生素组加用罗红霉素胶囊0.15 b.i.d.口服(此组均无大环内脂类抗生素过敏史), 中药治疗组加用中药清热解毒口服液或双黄连口服液10~20 ml t.i.d.口服。结果两组治疗时间均为3~7 d。罗红霉素治疗组治愈312例, 显效99例, 无效18例, 总有效率95.80%；中药治疗组治愈324例, 显效84例, 无效21例, 总有效率95.10%；两组疗效比较差异无统计学意义(P>0.05)。结论白细胞非升高性上呼吸道感染的治疗, 无需应用抗生素, 在对症、支持的基础上辅以中药治疗即可。

    【关键词】上呼吸道感染；病毒；抗生素；耐药性

    Clinical observation on 858 cases of non-elevated white blood cell of upper respiratory tract infectionYANG Hong-li, LIANG Wen, JIN Yan-hui. Beijing Puren Hospital, Beijing 100062, China

    【Abstract】Objective To investigate the effect of antibiotic therapy and traditional Chinese medicine in the treatment to non-elevated white blood cell of upper respiratory tract infection, in order to improve the rational use of drugs. Methods There were 858 cases of non-elevated white blood cell of upper respiratory tract infection treated with observation group who were randomly divided into the antibiotics treatment group in 429 cases and the antibiotic treatment group of Chinese medicine in 429 cases. Two groups were given general support and symptomatic treatment,antibiotic group was added with roxithromycin capsules 0.15 BID oral ( this group were not macrolide antibiotic allergy historiclly), group of traditional Chinese medicine was treated with traditional Chinese medicine for Qingre Jiedu oral liquid or 10-20 ml TID oral Shuanghuanglian oral liquid. Results Treatment of two groups lasted 3~7day. Roxithromycin treatment group: 312 cases were cured, 99 cases effective, 18 cases ineffective, the total effective rate was 95.80%; Chinese medicine treatment group: 324 cases were cured, 84 cases effective, 21 cases ineffective, the total effective rate was 95.10%; the effect difference of two groups have no statistical significance(P>0.05). Conclusion There is no need application of antibiotics treating upper respiratory tract infection, for using traditional Chinese medicine against the symptomatic is enough. ......