[摘要]目的：评价窒息新生儿心肌酶及肾功能水平及与窒息程度的关系。方法：86例窒息新生儿作为观察对象,重度窒息37例(A组), 轻度窒息49例(B组),正常新生儿45例为对照组(C 组)。于生后24 h采集静脉血检测谷草转氨酶(AST )、谷丙转氨酶(ALT)、乳酸脱氢酶(LDH)、羟丁酸脱氢酶(HBDH)、肌酸激酶(CK)及肌酸激酶心型同工酶(CK-MB)、肌酐(Cr)、尿素氮(BUN)、β2-微球蛋白(β2-MG)，各组间进行比较分析。结果：与正常新生儿相比，窒息新生儿心肌酶水平、Cr、BUN、β2-MG均显著升高,窒息程度越重，升高越明显。结论：窒息可引起新生儿心、肾功能损害，且与窒息程度密切相关。

    [关键词] 窒息；新生儿；心肌酶；肾功能

    [中图分类号] R446.11 [文献标识码]A [文章编号]1674-4721(2009)05(a)-046-02

    Clinical significance ofdeterminations of cardiac enzymes and renal function after asphyxia in neonates

    SUN Wei， LU Lihua

    (Department of Pediatrics, Fengxian CentralHospital,Shanghai201400，China)

    [Abstract] Objective: To evaluate the correlation between the changes of cardiac enzymes and renal function and the severity of asphyxia in neonates. Methods: Thirty-seven neonates with severe asphyxia(Group A), 49 cases with mild asphyxia( Group B) and 45 healthy infants( Group C ) were chosen. The levels of glutamic-oxalacetic transaminase(AST) ......